1,1'-Bis(di-tert-butylphosphino)ferrocene

CAS: 84680-95-5

Category: Organic Pharmaceutical Intermediates

PurityResearch Grade ≥97%; Catalyst Grade ≥98%; High-Purity Grade ≥99%
Molecular FormulaC26H40FeP2
Molecular Weight470.40
AppearanceOrange to deep red crystalline powder
Packaging1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle or laminated aluminum foil bag under nitrogen or argon
Testing IndicatorsAppearance — Visual inspection; Identification — ¹H NMR, ¹³C NMR and ³¹P NMR; Molecular weight confirmation — HRMS or MALDI-TOF MS; Purity — HPLC; Ligand integrity — ³¹P NMR; Iron content — ICP-OES or ICP-MS; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (ICH Q3C); Elemental analysis — CHN; Melting point — Capillary melting point apparatus.
Storage NotesStore tightly sealed under nitrogen or argon in a cool, dry, well-ventilated place. Protect from moisture, oxygen, direct sunlight and heat. Refrigerated storage at 2-8°C under inert atmosphere is recommended for long-term stability. Minimize exposure to air during weighing and transfer.
Lead Time10 days
A sterically hindered ferrocene-based bidentate diphosphine ligand widely used in homogeneous catalysis. Commonly employed with palladium, nickel, rhodium, iridium and other transition metals for Suzuki-Miyaura, Buchwald-Hartwig amination, Negishi, Kumada, Heck, Sonogashira and carbonylation reactions. Also used in pharmaceutical process development, asymmetric catalyst research, organometallic synthesis and fine chemical manufacturing.