2-(Dicyclohexylphosphino)biphenyl
CAS: 247940-06-3
Category: Organic Pharmaceutical Intermediates
| Purity | Catalyst Grade ≥98%; Research Grade ≥99%; HPLC Grade ≥99% |
| Molecular Formula | C24H31P |
| Molecular Weight | 350.48 |
| Appearance | White to off-white crystalline powder |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle or fluorinated HDPE bottle; customized bulk packaging available |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, ¹³C NMR and ³¹P NMR; Molecular weight — HRMS or LC-MS; Purity — HPLC (UV) and/or GC; Phosphine oxide impurity — ³¹P NMR or HPLC; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (ICH Q3C); Melting point — Capillary melting point determination; Elemental analysis — CHN elemental analysis. |
| Storage Notes | Store tightly sealed under an inert atmosphere (nitrogen or argon) in a cool, dry, well-ventilated location. Protect from air, moisture, direct sunlight, and heat sources. Recommended storage temperature is 2–8°C. Handle under inert gas whenever possible and reseal immediately after use. |
| Lead Time | 10 days |
A bulky, electron-rich biaryl monophosphine ligand extensively used in transition-metal catalysis. It is widely applied in palladium-catalyzed Buchwald-Hartwig amination, Suzuki-Miyaura, Negishi, Kumada, Stille, Sonogashira, and other C-C/C-N cross-coupling reactions. Frequently employed in catalyst development and pharmaceutical, agrochemical, and fine chemical synthesis due to its high catalytic activity and excellent steric properties.