N,O-bis(Trimethylsilyl)trifluoroacetamide
CAS: 25561-30-2
Category: Organosilicon Compounds
| Purity | Standard Grade ≥99%, With 1% TMCS ≥98%, With 10% TMCS ≥95% |
| Molecular Formula | C8H18F3NOSi2 |
| Molecular Weight | 257.4 |
| Appearance | Colorless to pale yellow liquid |
| Packaging | 5 g/glass bottle, 25 g/glass bottle, or 100 g/glass bottle |
| Testing Indicators | Appearance — Visual inspection; Density — ASTM D4052; Refractive index — ASTM D1218; Purity — GC; Identification — FTIR (Si–N, Si–O, CF₃–C=O bands), NMR; Moisture — Karl Fischer titration; Derivatization efficiency — Test with methanol or phenol by GC. |
| Storage Notes | Requires Refrigerated storage (0-10℃ or 2-8℃) due to its moisture and heat sensitivity. Keep the container tightly closed and store under an inert gas atmosphere. |
| Lead Time | 10 days |
A powerful and popular silylating reagent used primarily in analytical chemistry, especially for GC (Gas Chromatography) derivatization. It converts non-volatile or polar compounds into volatile, thermally stable trimethylsilyl (TMS) derivatives for easier analysis.