N,O-bis(Trimethylsilyl)trifluoroacetamide

CAS: 25561-30-2

Category: Organosilicon Compounds

PurityStandard Grade ≥99%, With 1% TMCS ≥98%, With 10% TMCS ≥95%
Molecular FormulaC8H18F3NOSi2
Molecular Weight257.4
AppearanceColorless to pale yellow liquid
Packaging5 g/glass bottle, 25 g/glass bottle, or 100 g/glass bottle
Testing IndicatorsAppearance — Visual inspection; Density — ASTM D4052; Refractive index — ASTM D1218; Purity — GC; Identification — FTIR (Si–N, Si–O, CF₃–C=O bands), NMR; Moisture — Karl Fischer titration; Derivatization efficiency — Test with methanol or phenol by GC.
Storage NotesRequires Refrigerated storage (0-10℃ or 2-8℃) due to its moisture and heat sensitivity. Keep the container tightly closed and store under an inert gas atmosphere.
Lead Time
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days
A powerful and popular silylating reagent used primarily in analytical chemistry, especially for GC (Gas Chromatography) derivatization. It converts non-volatile or polar compounds into volatile, thermally stable trimethylsilyl (TMS) derivatives for easier analysis.