Afatinib
CAS: 850140-72-6
Category: Kinase Inhibitors
| Purity | Pharmaceutical Grade, High-Purity Research Standard (≥98%). |
| Molecular Formula | C24H25ClFN5O3 |
| Molecular Weight | 485.94 |
| Appearance | Yellow to light yellow crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/lyophilized bottle. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Quinazoline dimers — SEC. |
| Storage Notes | Stored at -20°C in a tightly closed container under inert atmosphere, protected from light, moisture, and heat. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as an irreversible EGFR/HER2 tyrosine kinase inhibitor intermediate in the synthesis of oral therapies for EGFR-mutated non-small cell lung cancer.