Demei Chemicals Demei Chemicals

Larotrectinib sulfate

CAS: 1223405-08-0

Category: Kinase Inhibitors

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC21H24F2N6O6S
Molecular Weight526.51
AppearanceWhite to off-white crystalline powder
Packaging1 g/amber glass vial, 5 g/plastic bottle.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Sulfate test; Purity — Gradient RP-HPLC; Sulfate — Turbidimetry; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; TRK impurities — SEC.
Storage NotesStored at -20°C in a tightly closed container under inert atmosphere, protected from light and moisture.
Lead Time10 days
Used as a TRK inhibitor intermediate in the synthesis of oral targeted therapies for NTRK fusion-positive solid tumors.

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