Cabozantinib (S-malate)

CAS: 1140909-48-3

Category: Kinase Inhibitors

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC32H30FN3O10
Molecular Weight635.59
AppearanceWhite to off-white crystalline powder
Packaging1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Malate test; Purity — Gradient RP-HPLC; Malate — Ion chromatography; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Enantiomeric purity — Chiral HPLC.
Storage NotesStored in a cool, dry, and well-ventilated place in a tightly closed container, protected from light and moisture, away from incompatible materials, heat, and direct sunlight.
Lead Time
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days
Used as a multi-targeted tyrosine kinase inhibitor (MET, VEGFR, RET) in the formulation of oral therapies for advanced renal cell carcinoma and hepatocellular carcinoma.