Ponatinib
CAS: 943319-70-8
Category: Kinase Inhibitors
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C29H27F3N6O |
| Molecular Weight | 532.56 |
| Appearance | White to off-white crystalline powder |
| Packaging | 1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; BCR-ABL impurities — SEC. |
| Storage Notes | Stored in a cool, dry, and well-ventilated place in a tightly closed, light-resistant container, away from incompatible materials, heat, direct sunlight, and sources of ignition. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as a multi-targeted tyrosine kinase inhibitor (including BCR-ABL T315I mutant) in the synthesis of oral treatments for chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.