Lorlatinib
CAS: 1454846-35-5
Category: Kinase Inhibitors
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C21H19FN6O2 |
| Molecular Weight | 406.41 |
| Appearance | White to off-white crystalline powder |
| Packaging | 1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; ALK/ROS1 impurities — SEC. |
| Storage Notes | Stored in a cool, dry, and well-ventilated place in a tightly closed, light-resistant container, away from incompatible materials, heat, direct sunlight, and sources of ignition. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as a third-generation ALK/ROS1 tyrosine kinase inhibitor in the synthesis of targeted therapies for ALK-positive non-small cell lung cancer resistant to prior treatments.