4235-95-4 | DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine)

Chemical type

• Phospholipid
• Component of lipid bilayers

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• Unsaturated zwitterionic phospholipid (C18:1 chains)

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• Phospholipid

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Key properties

• Used to model cell membranes in simulations
• Provides hydrophobic environment for protein studies

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• Fluid-phase model membrane lipid (unsaturated tails)
• Zwitterionic over wide pH range (pKa phosphate ~2, ammonium ~9)
• Forms stable monolayers (collapse ~43–47 mN/m depending on subphase)

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• Forms liposomes (lipid bilayers)
• Slightly negative surface charge at pH 5.5
• Biocompatible

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• Membrane model in molecular dynamics simulations
• Used to study nanoparticle–membrane interactions

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• Standard model for fluid biological membranes in Langmuir-Blodgett studies
• Assessment of biocompatibility of Ch/HA/TiO₂ composites

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• Serves as a soft, sacrificial template for assembling polypeptide multilayers. The liposome's cavity is used to encapsulate molecules (HPTS, calcein) during fabrication.

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Classification by use

• Model lipids for membrane biophysics & biocompatibility testing

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• Template material for nanoencapsulation

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Toxic Effect of Fullerene and Its Derivatives upon the Transmembrane β2-Adrenergic Receptors, Molecules, 2022, 27(14), 4562
2. [Cite:2] The effect of chitosan/TiO2/hyaluronic acid subphase on the behaviour of 1,2-dioleoyl-sn-glycero-3-phosphocholine membrane, Biomaterials Advances, Volume 138, July 2022, 212934
3. [Cite:3] Multilayer nanoarchitectonics of polypeptide capsules with size-selective permeability, Journal of Colloid and Interface Science, Volume 708, 15 April 2026, 139842