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CasNo: 94-09-7
MF: C9H11NO2
Appearance: white odourless crystals
Indications and Usage |
Benzocaine is a colorless trapezial crystal. |
synthesis |
Benzocaine is produced by reduction of ethyl 4-nitrobenzoate with iron or by the acid-catalyzed esterification of 4-aminobenzoic acid with ethanol. |
Biological Functions |
Benzocaine is a PABA derivative used primarily for topical application to skin and mucous membranes. |
Safety Profile |
Poison by ingestion and intraperitoneal routes. |
Purification Methods |
Crystallise Benzocaine from EtOH/H2O or EtOH (m 93-94o), and dry it in air. [Beilstein 14 H 422, 14 IV 1129.] |
Structure and conformation |
Ethyl aminobenzoate, a para-aminobenzoate derivative (PABA) |
Chemical Structure |
Benzocaine, or ethyl 4-aminobenzoate, is an ester derived from 4-aminobenzoic acid. It is widely used as a topical anesthetic, antipruritic drug, allergen, and sensitizer. |
Brand name |
Americaine (Fisons); Baby Anbesol (Whitehall-Robins). |
InChI:InChI=1/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3/p+1
We have designed and synthesized four ne...
Highly dispersed Pd nanoparticles over c...
ethyl 4-nitrobenzoate
4-nitro-benzoic acid-(2,2,2-trichloro-ethyl ester)
2-(diethylamino)ethyl 2-chloro-4-nitrobenzoate
ethanol
ethyl 4-
ethyl 4-
4-(2-mercapto-ethylamino)-benzoic acid ethyl ester
ethyl 4-(N-butylamino)benzoate