What is the Octocrilene?

Octocrilene is Yellow viscous liquid, while it's Molecular Formula is C24H27NO2. Yellow viscous liquid Octocrylene is an ingredient used in sunscreens for its ability to absorb UV rays, protecting the skin from sun damage. It is chemically related to cinnamates. It can be used to boost SPF and improve water resistance in a given formulation. Octocrylene is photostable and can improve the photostability of other sunscreens. It is expensive and can present difficulties in formulation.

What is the CAS number for Octocrilene?

The CAS number of Octocrilene is 6197-30-4.

What is Octocrilene (6197-30-4) used for?

Octocrylene, a diarylmethane, is a yellow viscous liquid that is insoluble in water. It is an ester formed by the condensation of a diphenylcyanoacrylate with 2-ethylhexanol and is commonly used in sunscreens and cosmetics. Octocrylene is an effective oil-soluble liquid UV-B filter with excellent dissolving properties for crystalline UV filters.InChI:InChI=1/C24H27NO2/c1-3-5-12-19(4-2)18-27-24(26)22(17-25)23(20-13-8-6-9-14-20)21-15-10-7-11-16-21/h6-11,13-16,19H,3-5,12,18H2,1-2H3

What is the Octocrilene?

Octocrilene is Yellow viscous liquid, while it's Molecular Formula is C24H27NO2. Yellow viscous liquid Octocrylene is an ingredient used in sunscreens for its ability to absorb UV rays, protecting the skin from sun damage. It is chemically related to cinnamates. It can be used to boost SPF and improve water resistance in a given formulation. Octocrylene is photostable and can improve the photostability of other sunscreens. It is expensive and can present difficulties in formulation.

What is the CAS number for Octocrilene?

The CAS number of Octocrilene is 6197-30-4.

What is Octocrilene (6197-30-4) used for?

Octocrylene, a diarylmethane, is a yellow viscous liquid that is insoluble in water. It is an ester formed by the condensation of a diphenylcyanoacrylate with 2-ethylhexanol and is commonly used in sunscreens and cosmetics. Octocrylene is an effective oil-soluble liquid UV-B filter with excellent dissolving properties for crystalline UV filters.InChI:InChI=1/C24H27NO2/c1-3-5-12-19(4-2)18-27-24(26)22(17-25)23(20-13-8-6-9-14-20)21-15-10-7-11-16-21/h6-11,13-16,19H,3-5,12,18H2,1-2H3

Octocrilene

Basic information

Product Name:Octocrilene
CasNo.:6197-30-4
MF:C₂₄H₂₇NO₂

Physical and Chemical Properties

Purity:99%
Melting Point:-10 °C
Appearance:Yellow viscous liquid

Inquiry

Product Details

CasNo： 6197-30-4

MF： C₂₄H₂₇NO₂

Appearance： Yellow viscous liquid

Quality Factory Sells Top Purity 99% Octocrilene 6197-30-4 with Safe Delivery

Molecular Formula:C24H27NO2
Molecular Weight:361.484
Appearance/Colour:Yellow viscous liquid
Vapor Pressure:2.56E-09mmHg at 25°C
Melting Point:-10 °C
Refractive Index:n20/D 1.567(lit.)
Boiling Point:478.5 °C at 760 mmHg
Flash Point:239.5 °C
PSA：50.09000
Density:1.055 g/cm³
LogP:5.77168

Octocrilene(Cas 6197-30-4) Usage

Uses	Octocrylene is a common UV absorber. It is widely used in sunscreen products and can effectively absorb UV rays, reduce UV damage to the skin, and reduce the risk of sunburn and tanning. Octocrylene has good stability and compatibility and is often used in combination with other sunscreen ingredients to provide more comprehensive sun protection. It is usually prepared by chemical synthesis. For example, in many sunscreens and sunscreen sprays, octocrylene is an important component to help people protect against UV rays when they are outdoors.
Air & Water Reactions	Insoluble in water.
Fire Hazard	Flash point data for Octocrilene are not available. Octocrilene is probably combustible.
Flammability and Explosibility	Nonflammable
Contact allergens	Octocrylene is an anti-UVB filter used in cosmetics that may induce photoallergic contact dermatitis.
Safety Profile	Low toxicity by ingestion. Whenheated to decomposition it emits toxic vapors of NOx.
Definition	ChEBI: Octocrylene is a diarylmethane. It is an ester formed by the condensation of a diphenylcyanoacrylate with 2-ethylhexanol, used in sunscreens and cosmetics.
General Description	Yellow viscous liquid. Insoluble in water. Octocrylene is a new emerging photoallergen.

InChI:InChI=1/C24H27NO2/c1-3-5-12-19(4-2)18-27-24(26)22(17-25)23(20-13-8-6-9-14-20)21-15-10-7-11-16-21/h6-11,13-16,19H,3-5,12,18H2,1-2H3

6197-30-4 Relevant articles

Review of the safety of octocrylene used as an ultraviolet filter in cosmetics

E. Berardesca, T. Zuberbier, M. Sanchez Viera, M. Marinovich

Journal of the European Academy of Dermatology and Venereology, Volume33, IssueS7 Special Issue:An Evidence‐Based Safety Review of Four Questioned Cosmetic Ingredients. This supplement was supported by a grant from Cosmetique Active International November 2019 Pages 25-33

The available data show that octocrylene does not have any endocrine disruption potential. It is a rare sensitizer, photocontact allergy is more frequent and it is considered consecutive to photosensitization to ketoprofen. Based on these results, octocrylene can be considered as safe when used as a UV filter in cosmetic products at a concentration up to 10%.

Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products

C. A. Downs*Joseph C. DiNardoDidier StienAlice M. S. RodriguesPhilippe Lebaron

, Chem. Res. Toxicol. 2021, 34, 4, 1046–1054

Octocrylene generates benzophenone through a retro-aldol condensation. In vivo, up to 70% of the benzophenone in these sunscreen products may be absorbed through the skin. U.S. FDA has established a zero tolerance for benzophenone as a food additive. In the United States, there were 2999 SPF products containing octocrylene in 2019. The safety of octocrylene as a benzophenone generator in SPF or any consumer products should be expeditiously reviewed by regulatory agencies.

A NOVEL PROCESS FOR THE PREPARATION OF 2-CYANO- 3,3- DIARYLACRYLATES

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Page/Page column 9; 10, (2014/11/13)

The present invention relates to a novel...

6197-30-4 Process route

: 119-61-9
benzophenone

: 13361-34-7
2'-ethylhexyl cyanoacetate

: 6197-30-4,80135-31-5
octocrylene

Conditions

Conditions	Yield
With ammonium acetate; acetic acid; In water; at 85 - 90 ℃; for 16h; under 400 - 420 Torr; Reagent/catalyst;	76.3%
With propionic acid; ammonium acetate; In n-heptane; at 110 ℃; for 5h; under 760.051 Torr; Product distribution / selectivity;	66.18%

: 104-76-7
2-Ethylhexyl alcohol

: 5232-99-5
etocrylene

: 6197-30-4,80135-31-5
octocrylene