Demei Chemicals Demei Chemicals

Crizotinib (hydrochloride)

CAS: 1415560-69-8

Category: Kinase Inhibitors

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC21H23Cl3FN5O
Molecular Weight486.8
AppearanceWhite to off-white crystalline powder
Packaging1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Chloride test; Purity — Gradient RP-HPLC; pH — Potentiometry; Chloride — Argentometric titration; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration.
Storage NotesStored in a cool, dry, and well-ventilated place in a tightly closed, light-resistant container, away from incompatible materials, heat, direct sunlight, and moisture.
Lead Time
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days
Used as a selective inhibitor of ALK, ROS1, and MET tyrosine kinases in the synthesis of targeted therapies for ALK-positive non-small cell lung cancer and other oncogenic driver mutations.

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