Larotrectinib
CAS: 1223403-58-4
Category: Kinase Inhibitors
| Purity | Research Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5% |
| Molecular Formula | C21H22F2N6O2 |
| Molecular Weight | 428.44 |
| Appearance | white to off-white crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/lyophilized bottle. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Chiral HPLC; Purity — Gradient RP-HPLC; Enantiomeric purity — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; TRK impurities — SEC. |
| Storage Notes | Stored at -20°C in a tightly closed container under inert atmosphere, protected from light and moisture. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as a tropomyosin receptor kinase (TRK) inhibitor intermediate in the synthesis of targeted anticancer agents for NTRK gene fusion-positive tumors.