Demei Chemicals Demei Chemicals

Crizotinib

CAS: 877399-52-5

Category: Kinase Inhibitors

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC21H22Cl2FN5O
Molecular Weight450.34
AppearanceWhite to off-white crystalline powder
Packaging1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Chiral HPLC; Purity — Gradient RP-HPLC; Enantiomeric purity — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; ALK inhibitor impurities — SEC.
Storage NotesStored in a cool, dry, and well-ventilated place in a tightly closed container, protected from light and moisture, away from incompatible materials, heat, and direct sunlight.
Lead Time
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days
Used as a multi-targeted tyrosine kinase inhibitor (ALK, MET, ROS1) in the formulation of precision oncology drugs for treating advanced ALK-rearranged tumors.

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