Selpercatinib

CAS: 2152628-33-4

Category: Kinase Inhibitors

PurityResearch Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC29H31N7O3
Molecular Weight525.6
Appearancewhite to off-white crystalline powder
Packaging1 g/amber glass vial, 5 g/plastic bottle.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; RET kinase impurities — SEC.
Storage NotesStored in a cool, dry place at room temperature (20-25°C) in a tightly closed container, protected from light and moisture.
Lead Time
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days
Used as a selective RET kinase inhibitor intermediate in the synthesis of targeted therapies for RET fusion-positive non-small cell lung cancer and thyroid cancers.