9005-35-0 | Calcium Alginate

Chemical type

• Polysaccharide derivative cross-linked with calcium ions
• pH-sensitive gel polymer

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• Polysaccharide gel (water-insoluble alginate salt derived from sodium alginate)

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Key properties

• pH-responsive swelling and degradation
• Enzyme-responsive in colonic environment
• Stable and intact in acidic gastric conditions
• Hydrates and increases porosity at neutral pH
• Impedes diffusion of oxidative species (e.g., O₂)
• Enhances thermal, photo, and oxidative stability of encapsulants

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• High hygroscopicity and moisture adsorption capacity (up to 1.009 g/g in composites with additives)
• Porous structure enhanced by freeze-drying and additives like PVP
• Good adsorption kinetics, especially when combined with silica gel or expanded graphite
• Decreased pore volume and diameter with higher Ca²⁺ concentration due to excessive cross-linking
• Improved mechanical properties (e.g., compressive strength) at higher CaCl₂ concentrations
• Thermal stability suitable for building applications

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• Shell in core-shell microspheres for colon-targeted release
• Protection against premature drug release in stomach
• Sustained, site-specific delivery at inflammatory sites
• Encapsulation of PO-SECs in Ca-Alg@PO-SECs system
• Blocking penetration of simulated gastric fluid

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• Moisture-adsorbing matrix in hygroscopic phase change composites (HPCC)
• Regulates indoor humidity and temperature in buildings
• Integrated with PCMs to prevent leakage and enhance performance
• Applied in gypsum boards or wall materials to increase moisture buffer value (MBV) up to 9.3 g/(m²·%RH)

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Classification by use

• Biocompatible polymers for gastrointestinal drug delivery
• pH-sensitive materials in controlled-release formulations
• Protective gels in natural drug carriers

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• Hygroscopic materials
• Building energy efficiency materials
• Composite matrices for phase change applications

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Engineered Sporopollenin Exine Capsules for Colon-Targeted Delivery and Antioxidant Therapy of Calcium Alginate in Ulcerative Colitis, Antioxidants, 2026, 15(1), 116
2. [Cite:2] Study on synthesis and hygrothermal performance of calcium alginate-based moisture-adsorbing phase change composite, Next Materials, Volume 10, January 2026, 101401